PicoBlog

Conjugated equine estrogens (CEE), also known as Premarin, named because it comes from pregnant mares urine, was the industry standard for menopause hormone therapy for years until all estrogens took a hit with the Women’s Health Initiative (WHI). Once the dust settled, the recommended first-line therapy for symptoms of menopause became transdermal estradiol due to the lower risk of blood clots. However, there has been a renewed interest in Premarin due to the fact that it is associated with a lower long-term risk of breast cancer (when used without a progestin), and it is available in combination with bazedoxifene as another option for menopause hormone therapy without progesterone or a progestin (read more about that option here).

Frat king Will Ferrell plays the hits during surprise DJ set at college tailgate party; A24 is making a TV series about Paris Hilton’s life; Malia Obama is a new menswear icon; and Reformation is collaborating with the New York City Ballet — peak balletcore! WHEN DID ROCK CONCERTS BECOME TAME? THANK ALCOHOL-FREE GEN Z, wsj “Generation Z and millennials pe… ncG1vNJzZmiZlqmys7%2FCoaaopF6owqO%2F05qapGaTpLpwvI6pqZ6ooK56r7XRr5inmV2Wu6V5waKeZqeZoQ%3D%3D

After being business partners for nearly 10 years, Casey Dunlavey and Seth Clark sometimes bicker like an old married couple. Clark wanted to save the original glass-fronted door from their first business, Lock 32 Brewing in the village of Pittsford. Dunlavey would’ve preferred to throw it away. Clark ultimately won and Dunlavey, at least begrudgingly, must admit Clark was right. “I made fun of Seth for eight years for keeping it,” Dunlavey said.

Guest post alert! Jeremy here, and I’m very excited that Courtney LeSueur is expanding her contributions to this newsletter via the written word. Courtney is kinda the creative director of this newsletter, since she came up with our amazing Dusty logo, which allowed me to go crazy with some subscriber merch. Anyway, since you already know she's an amazingly talented designer, you probably won't be surprised to hear that she just created a smattering of Drop Dead Gorgeous shirts, mugs, and stickers for Super Yaki.

Mausam Indian restaurant is on pace to soft-open sometime in the coming days at 3167 W. Colorado Ave. (a former IHOP) in between OCC and Manitou Springs. This might normally land as run-of-the-mill restaurant news — as the Springs doesn’t exactly lack fine Indian options now. But there’s something quite different about Mausam, in that it’s introducing a Michelin-awarded chef to town. ChefDharam Singh has arrived from a recent stint in Denmark that followed time across China.

For a brief moment at the start of Black Lives Matter protests in the spring, Adidas extended an olive branch to Nike on Twitter where it quote tweeted a moving Nike campaign. (And we all agree the reverse would never have occurred, correct?) It felt nice but still weird, not unlike a disturbance in the universe and yet, it took just seven months for all to return to normal with the two brands taking pot shots from each other on opposite sides on the fence.

I write mostly about God now. I used to write about intuitive eating, then I became a rebellious libertarian during covid, which made most of my former readers hate me. Then I converted (back) to Christianity. Yes it's all been very strange. By Caroline Dooner · Over 19,000 subscribersNo thanks“Funny, frustrating, makes you think.” “My first paid subscription. Caroline discusses the "stuff" that must not be spoken about - demons and her reconversion to Jesus.

It’s damn near impossible to imagine the American indie film revolution of the late 20th century taking place without Christine Vachon. But even as the movement began to dissipate in the early Aughts, the result of production houses and distributors being bought up and shuttered by Hollywood studios, she pressed on. Today, it’s fair to say few producers in the world have shepherded as many great films into existence as she has - many of which have influenced legions of other filmmakers, including myself, quite literally changing the kinds of stories that show up on the big screen.

SET 1: Makisupa Policeman -> Maze, Water in the Sky, Guyute, Guelah Papyrus, Limb By Limb, Horn, Run Like an Antelope SET 2: Timber (Jerry the Mule) > Piper, Vultures > My Soul, You Enjoy Myself, Character Zero ENCORE: The Squirming Coil Listen on phish.in The second half of Marc Allan’s infamous quote, “Phish could urinate in its fans’ ears and tell them it’s music,” is perhaps even more wounding: “The fans, in turn, will be there with tape recorders to capture the moment.